Re: Consensus definition for placental fetal growth restriction: a Delphi procedure

Placental Angiogenesis and Fetal Growth Restriction

Placental insufficiency and fetal growth restriction.

OBJECTIVES Fetal growth restriction is defined as a pathologic decrease in the rate of fetal growth. The most frequent etiology for late onset fetal growth restriction is uteroplacental dysfunction which is due to inadequate supply of nutrients and oxygen to support normal aerobic growth of the fetus. However, for symmetrical IUGR, fetal chromosomal anomalies, structural anomalies and fetal inf...

New Definition of Fetal Growth Restriction: Consensus Regarding a Major Obstetric Complication.

Fetal growth restriction (FGR) affects 5–10% of all pregnancies, and it is the second leading cause of perinatal mortality, accounting for 30% of stillbirths; it leads to prematurebirths and intrapartum asphyxia.1 Fetuses with FGR have an increased risk for perinatal morbidity and mortality, impaired neurological and cognitive developmentduring childhood and adolescence, and cardiovascular and ...

Searching for an operational definition of frailty: a Delphi method based consensus statement: the frailty operative definition-consensus conference project.

BACKGROUND There is no consensus regarding the definition of frailty for clinical uses. METHODS A modified Delphi process was used to attempt to achieve consensus definition. Experts were selected from different fields and organized into five Focus Groups. A questionnaire was developed and sent to experts in the area of frailty. Responses and comments were analyzed using a pre-established str...

Placental Adaptations in Growth Restriction

The placenta is the primary interface between the fetus and mother and plays an important role in maintaining fetal development and growth by facilitating the transfer of substrates and participating in modulating the maternal immune response to prevent immunological rejection of the conceptus. The major substrates required for fetal growth include oxygen, glucose, amino acids and fatty acids, ...